Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207651 | 0.91 | PTGER1 (0.49) | MAPK14PTGER1PTGDRPPARAKDM5B | |
| SCHEMBL5202766 | 0.90 | MAPK14 (0.49) | MAPK14PTGER1MAOB | |
| SCHEMBL5203740 | 0.85 | CYP1A1 (0.42) | MAPK14PTGER1MAOB | |
| SCHEMBL5203927 | 0.82 | MAPK14 (0.49) | MAPK14PTGER1MAOB | |
| SCHEMBL3523399 | 0.79 | MAPK14 (0.51) | MAPK14PTGER1MRGPRX4 | |
| SCHEMBL3524202 | 0.75 | MAPK14 (0.59) | MAPK14MAOB | |
| SCHEMBL5322585 | 0.74 | MAPK14 (0.56) | MAPK14PTGER1 | |
| SCHEMBL5320422 | 0.74 | MAPK14 (0.50) | MAPK14PTGER1 | |
| SCHEMBL3525402 | 0.73 | MAPK14 (0.49) | MAPK14PTGER1MAOB | |
| SCHEMBL5205590 | 0.73 | MAOB (0.39) | MAPK14PTGER1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |