Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280738 | 0.85 | MCHR1 (0.42) | MAOBMAPK14IDO1AGXT | |
| SCHEMBL5207452 | 0.85 | MEN1 (0.39) | MAOBMAPK14IDO1AGXTPTGER1 | |
| SCHEMBL5203025 | 0.81 | HTR2A (0.38) | MAOBMAPK14 | |
| SCHEMBL5203740 | 0.81 | CYP1A1 (0.42) | MAOBMAPK14PTGER1CYP1A1CYP1A2 | |
| SCHEMBL5203024 | 0.81 | MAOB (0.37) | MAOBMAPK14IDO1AGXTPTGER1 | |
| SCHEMBL5204954 | 0.80 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL5202334 | 0.80 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL5203927 | 0.76 | MAPK14 (0.49) | MAOBMAPK14PTGER1 | |
| SCHEMBL5202380 | 0.75 | MAOB (0.42) | MAOBMAPK14IDO1AGXTPTGER1 | |
| SCHEMBL5207651 | 0.74 | PTGER1 (0.49) | MAPK14PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |