Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.62 |
| ▸ | GRK5 | P34947 | 2/20 | 0.62 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 14/20 | 0.50 |
| ▸ | CA9 | Q16790 | 14/20 | 0.50 |
| ▸ | CA2 | P00918 | 13/20 | 0.50 |
| ▸ | CA1 | P00915 | 11/20 | 0.50 |
| ▸ | CA7 | P43166 | 10/20 | 0.50 |
| ▸ | CA4 | P22748 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834818 | 1.00 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7023285 | 0.81 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL1725776 | 0.77 | RET (1.00) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL3961225 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7381362 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL9620282 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL11155230 | 0.76 | RET (0.61) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7287038 | 0.75 | RET (0.56) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7778266 | 0.74 | RET (0.46) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7280743 | 0.74 | RET (0.59) | RETGRK5TYRO3DYRK1BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6776930-B2 | POLYMER BONDED TO DYE | EASTMAN KODAK COMPANY | 2004-08-17 | — | — | US | claimed |
| US-20010023938-A1 | Polymer bonded to dye | ALLEN MAX (US) | 2001-09-27 | — | — | US | claimed |
| US-6197223-B1 | REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND | EASTMAN CHEMICAL COMPANY | 2001-03-06 | — | — | US | claimed |
| EP-0948570-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1999-10-13 | — | — | EP | claimed |
| WO-1998023690-A9 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | — | 1998-09-17 | — | — | WO | claimed |
| WO-1998023690-A1 | METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1998-06-04 | — | — | WO | claimed |
| US-20230353959-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |
| WO-2021222556-A1 | PI3K-α INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| EP-1739135-A2 | Colorant compounds containing copolymerizable vinyl groups | Eastman Chemical Company (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1307515-B1 | COLORANT COMPOUNDS CONTAINING COPOLYMERIZABLE VINYL GROUPS | EASTMAN CHEM CO (US) | 2006-06-28 | — | — | EP | disclosed |
| US-7060829-B2 | Colorant compounds containing copolymerizable vinyl groups | EASTMAN CHEMICAL COMPANY (US) | 2006-06-13 | — | — | US | disclosed |
| US-7030244-B2 | Colorant compounds containing copolymerizable vinyl groups | EASTMAN CHEMICAL COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| EP-0550112-A1 | 2-Saccharinylmethyl aryl and aryloxy acetates useful as proteolytic enzyme inhibitors and pharmaceutical compositions contaning them | STERLING WINTHROP INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| EP-0549073-A1 | Novel 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5187173-A | Degenerative diseases such as emphysema, rheumatoid arthritis, pancreatitis, cyctic fibrosis and skin disorders | STERLING WINTHROP INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5128339-A | Emphysema, rheumatoid arthritis, pancreatitis | STERLING WINTHROP INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0483928-A1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use | STERLING WINTHROP INC. (US) | 1992-05-06 | — | — | EP | disclosed |
| US-4404230-A | ARTICIFIAL SWEETENERS | DR. KARL THOMAE GMBH (DE) | 1983-09-13 | — | — | US | disclosed |
| US-3878189-A | Azo dye compounds from amino-1,2-benzisothiazolon-1,1-dioxides | CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK | 1975-04-15 | — | — | US | disclosed |