Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.62 |
| ▸ | GRK5 | P34947 | 2/20 | 0.62 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 13/20 | 0.54 |
| ▸ | CA9 | Q16790 | 13/20 | 0.54 |
| ▸ | CA2 | P00918 | 12/20 | 0.54 |
| ▸ | CA1 | P00915 | 10/20 | 0.54 |
| ▸ | CA4 | P22748 | 9/20 | 0.54 |
| ▸ | CA7 | P43166 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834818 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL5204879 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL3961225 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL1725776 | 0.77 | RET (1.00) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7023285 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7381362 | 0.77 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7279160 | 0.77 | RET (0.57) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL11155230 | 0.76 | RET (0.61) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7280743 | 0.74 | RET (0.59) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL29700163 | 0.74 | RET (0.46) | RETGRK5TYRO3DYRK1BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143039-A | Benzo five-membered nitrogen ring compound, preparation method and medical application thereof | 山东大学 | 2023-12-01 | — | — | CN | disclosed |
| US-20140135215-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8629284-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-5104441-A | HERBICIDAL SULFONAMIDES AND THEIR USE TO INFLUENCE PLANT GROWTH | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| US-5100459-A | Herbicides, plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| US-5032167-A | Herbicides | BASF (DE) | 1991-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135215-A1 | CHEMICAL COMPOUNDS | CBR3, CCNY, C3AR1 | RET 2335/4885GRK5 2114/4885TYRO3 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.