Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452511 | 0.85 | GAA (0.58) | GAAALDH1A1RCE1F10TLR4 | |
| SCHEMBL1049509 | 0.83 | ALDH1A1 (0.75) | GAAALDH1A1RCE1F10TLR4 | |
| SCHEMBL921481 | 0.81 | DPP4 (0.58) | GAAALDH1A1F10DPP4LOXL2 | |
| SCHEMBL922401 | 0.81 | FFAR1 (0.51) | GAAALDH1A1F10DPP4LOXL2 | |
| SCHEMBL922873 | 0.81 | F10 (0.50) | F10DPP4LOXL2MAOBLOX | |
| SCHEMBL921026 | 0.81 | ALDH1A1 (0.53) | GAAALDH1A1F10KDM4EMAOB | |
| Ammonia Solution, Strong SCHEMBL10884991 | 0.81 | ALDH1A1 (0.72) | GAAALDH1A1RCE1F10TLR4 | |
| SCHEMBL6289782 | 0.81 | ALDH1A1 (0.72) | GAAALDH1A1RCE1F10TLR4 | |
| SCHEMBL6290404 | 0.81 | ALDH1A1 (0.72) | GAAALDH1A1RCE1F10TLR4 | |
| SCHEMBL1270999 | 0.81 | ALDH1A1 (0.72) | GAAALDH1A1RCE1F10TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |