Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7726049 | 0.99 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAKCNH2NCF1 | |
| Trifluoroacetic Acid SCHEMBL7726051 | 0.95 | MTNR1A (0.45) | MTNR1AMTNR1BKCNH2 | |
| Trifluoroacetic Acid SCHEMBL7728891 | 0.95 | MTNR1A (0.45) | MTNR1AMTNR1BKCNH2 | |
| SCHEMBL5206940 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAKCNH2NCF1 | |
| SCHEMBL5242818 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAKCNH2NCF1 | |
| SCHEMBL6607712 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAKCNH2NCF1 | |
| SCHEMBL7460734 | 0.86 | MTNR1A (0.47) | MTNR1AMTNR1BKCNH2NCF1 | |
| SCHEMBL8128824 | 0.85 | MTNR1A (0.46) | MTNR1AMTNR1BKCNH2NCF1 | |
| SCHEMBL6964736 | 0.85 | MTNR1A (0.46) | MTNR1AMTNR1BKCNH2NCF1 | |
| SCHEMBL6966393 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BKCNH2NCF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484328-B1 | Derivatives of quinolyl-propyl-piperidine and their use as antimicrobial agents | AVENTIS PHARMA SA (FR) | 2007-05-02 | — | — | EP | disclosed |
| EP-1484328-A1 | Derivatives of quinolyl-propyl-piperidine and their use as antimicrobial agents | Aventis Pharma S.A. (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-B1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |