Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294455 | 0.73 | CYP2C19 (0.47) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL11659911 | 0.73 | HDAC1 (0.49) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL7247132 | 0.70 | MAPK13 (0.56) | HDAC1HDAC3HDAC2MAPK1MAPT | |
| SCHEMBL13727656 | 0.69 | HDAC1 (0.45) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL19775165 | 0.68 | MAPT (0.43) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL2312445 | 0.68 | HDAC1 (0.40) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL1269273 | 0.67 | MAPT (0.46) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL29666932 | 0.67 | MAPT (0.46) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL28857943 | 0.67 | HDAC1 (0.50) | HDAC1HDAC3HDAC2MAPK1PTGS1 | |
| SCHEMBL653241 | 0.66 | HDAC3 (0.68) | HDAC1HDAC3HDAC2MAPK1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |