Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 16/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250263 | 0.84 | HDAC3 (0.64) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL31174164 | 0.84 | HDAC3 (0.64) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL3071688 | 0.84 | HDAC3 (0.64) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL9515806 | 0.84 | NPC1 (0.67) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL17796923 | 0.84 | HDAC3 (0.50) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL1226530 | 0.83 | SMN1; SMN2 (0.54) | HDAC3HDAC1HDAC2MAPK1NPC1 | |
| SCHEMBL29519193 | 0.83 | SMN1; SMN2 (0.54) | HDAC3HDAC1HDAC2MAPK1NPC1 | |
| SCHEMBL11048016 | 0.83 | HDAC3 (0.63) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL407834 | 0.81 | HDAC1 (1.00) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL30363156 | 0.81 | HDAC1 (1.00) | HDAC3HDAC1HDAC2MAPK1NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293718-B1 | SUBSTITUTED AMINOPHENYL CARBAMATE | BAYER AG (DE) | 1993-02-03 | — | — | EP | claimed |
| EP-0293718-A2 | Substituted aminophenyl carbamate | BAYER AG (DE) | 1988-12-07 | — | — | EP | claimed |
| WO-2024148329-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS TO ADIPOSE TISSUE | Arrowhead Pharmaceuticals, Inc. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023242070-A9 | ANTIMICROBIAL COMPOUNDS | AKTHELIA PHARMACEUTICALS (IS) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024123929-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BIOVENTURES, LLC (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-4093730-B1 | HDAC DEGRADER | UNIV LEICESTER (GB) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023242070-A1 | ANTIMICROBIAL COMPOUNDS | AKTHELIA PHARMACEUTICALS (IS) | 2023-12-21 | — | — | WO | disclosed |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-11655260-B2 | Heterocyclic compounds as arginase inhibitors | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20230120211-A1 | HDAC Degrader | UNIVERSITY OF LEICESTER (GB) | 2023-04-20 | — | — | US | disclosed |
| US-20230113588-A1 | METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2023-04-13 | — | — | US | disclosed |
| US-6090525-A | PHOTOSENSITIVE POLYIMIDE COATING AGENT COMPOSITION WITH BOTH GOOD VISCOSITY STABILITY AT ROOM TEMPERATURE WITH LAPSE OF TIME AND GOOD PHOTOSENSITIVE PERFORMANCE | TORAY INDUSTRIES, INC. (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0878740-A1 | Radiation sensitive polymer composition | TORAY INDUSTRIES, INC. (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0293718-B1 | SUBSTITUTED AMINOPHENYL CARBAMATE | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |
| EP-0293718-B1 | SUBSTITUTED AMINOPHENYL CARBAMATE | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |
| EP-0293718-A2 | Substituted aminophenyl carbamate | BAYER AG (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0293718-A2 | Substituted aminophenyl carbamate | BAYER AG (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0293718-A2 | Substituted aminophenyl carbamate | BAYER AG (DE) | 1988-12-07 | — | — | EP | disclosed |
| US-4241218-A | TOXIC AGENTS FOR CHEMICAL WARFARE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1980-12-23 | — | — | US | disclosed |
| US-3979202-A | Meta-bifunctional benzenes and herbicidal compositions | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655260-B2 | Heterocyclic compounds as arginase inhibitors | ARG1, ARG2, PRMT1 | HDAC3 195/4885HDAC1 62/4885HDAC2 104/4885 |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | SOD1, ME3, ME2 | HDAC3 1378/4885HDAC1 800/4885HDAC2 1796/4885 |
| US-20230120211-A1 | HDAC Degrader | HDAC1, HDAC11, HDAC3 | HDAC3 3/4885HDAC1 1/4885HDAC2 4/4885 |
| US-20230113588-A1 | METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAMS) AND USES THEREOF | GRM3, GRM2, GRM1 | HDAC3 239/4885HDAC1 657/4885HDAC2 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.