⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183503 | 0.57 | — | — | |
| SCHEMBL8751852 | 0.56 | — | — | |
| SCHEMBL22698345 | 0.50 | — | — | |
| SCHEMBL1107779 | 0.50 | — | — | |
| SCHEMBL21374382 | 0.48 | — | — | |
| SCHEMBL8373132 | 0.46 | — | — | |
| SCHEMBL1024758 | 0.42 | — | — | |
| SCHEMBL321091 | 0.42 | — | — | |
| SCHEMBL16002311 | 0.42 | — | — | |
| SCHEMBL16534479 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499623-B1 | PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-¬(2-METHYL-1H-IMIDAZOL-1-YL)METHYL|-4H-CARBAZOL-4-ONE | TEVA GYOGYSZERGYAR ZARTKOERUEE (HU) | 2007-06-13 | — | — | EP | disclosed |
| US-20060252942-A1 | Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one | MOLNAR SANDOR | 2006-11-09 | — | — | US | disclosed |
| US-7098345-B2 | Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one | TEVA Gyógyszergyár Zárkörüen Müködö Részvénytársaság (HU) | 2006-08-29 | — | — | US | disclosed |
| US-20050020655-A1 | Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2005-01-27 | — | — | US | disclosed |
| EP-1499623-A1 | PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-[(2-METHYL-1H-IMIDAZOL-1-YL)METHYL]-4H-CARBAZOL-4-ONE | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093281-A1 | PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-[(2-METHYL-1H-IMIDAZOL-1-YL)METHYL]-4H-CARBAZOL-4-ONE | BIOGAL GYOGYSZERGYAR RT. (HU) | 2003-11-13 | — | — | WO | disclosed |