Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20337746 | 0.90 | GABRP (0.41) | RARBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24079171 | 0.87 | RARB (0.39) | RARBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14831507 | 0.83 | HCAR2 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8328355 | 0.82 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19840685 | 0.81 | GABRP (0.40) | RARBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25171290 | 0.77 | HCAR2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7386044 | 0.75 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18400870 | 0.75 | HSP90AA1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24908448 | 0.74 | GABRP (0.46) | RARBGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9500202 | 0.74 | GABRP (0.50) | RARBGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180520-B1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2007-06-20 | — | — | EP | disclosed |