Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 3/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208483 | 0.92 | SCN9A (0.36) | TSPOPTGESALOX5HDAC1SCN9A | |
| SCHEMBL5204846 | 0.87 | HDAC1 (0.42) | TSPOPTGESALOX5FFAR1HDAC1 | |
| SCHEMBL5205817 | 0.86 | PTGER4 (0.40) | TSPOSCN9APTGER4 | |
| SCHEMBL5204784 | 0.86 | PTGER4 (0.40) | TSPOSCN9APTGER4 | |
| SCHEMBL5205558 | 0.86 | HDAC1 (0.42) | TSPOPTGESALOX5FFAR1HDAC1 | |
| SCHEMBL5205723 | 0.85 | HDAC1 (0.41) | TSPOPTGESALOX5FFAR1HDAC1 | |
| SCHEMBL5201617 | 0.83 | HDAC1 (0.44) | TSPOPTGESALOX5HDAC1 | |
| SCHEMBL5205929 | 0.80 | PPARG (0.40) | TSPOPTGESALOX5HDAC1SCN9A | |
| SCHEMBL5206532 | 0.79 | SCN9A (0.39) | TSPOSCN9APTGER4 | |
| SCHEMBL5204339 | 0.79 | SCN9A (0.39) | TSPOSCN9APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |