Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.41 |
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310384 | 0.93 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL5211033 | 0.91 | HTT (0.42) | PPARGPPARAFFAR1MAPTTP53 | |
| SCHEMBL2522398 | 0.89 | PPARG (0.42) | PPARGPPARAFFAR1MAPTTP53 | |
| SCHEMBL2522393 | 0.89 | PPARG (0.42) | PPARGPPARAFFAR1MAPTTP53 | |
| SCHEMBL5209231 | 0.89 | PPARG (0.41) | PPARGPPARAFFAR1MAPTTP53 | |
| SCHEMBL5278398 | 0.88 | PPARG (0.50) | PPARGPPARAFFAR1MAPTTP53 | |
| SCHEMBL5210918 | 0.83 | PPARG (0.43) | PPARGPPARAFFAR1ALDH1A1LMNA | |
| SCHEMBL2518462 | 0.83 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL2518456 | 0.83 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5213251 | 0.83 | TP53 (0.49) | PPARGPPARAFFAR1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |