Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.41 |
| ▸ | PPARA | Q07869 | 16/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515830 | 0.90 | PPARG (0.42) | PPARGPPARAFFAR1TP53MAPT | |
| SCHEMBL2515827 | 0.90 | PPARG (0.42) | PPARGPPARAFFAR1TP53MAPT | |
| SCHEMBL5206428 | 0.89 | PPARG (0.41) | PPARGPPARAFFAR1TP53MAPT | |
| SCHEMBL5211033 | 0.89 | HTT (0.42) | PPARGPPARAFFAR1TP53MAPT | |
| SCHEMBL5278398 | 0.86 | PPARG (0.50) | PPARGPPARAFFAR1TP53MAPT | |
| SCHEMBL5206107 | 0.84 | PPARG (0.44) | PPARGPPARAFFAR1 | |
| SCHEMBL5310384 | 0.84 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL5213073 | 0.82 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL5213251 | 0.81 | TP53 (0.49) | PPARGPPARAFFAR1TP53MAPT | |
| SCHEMBL2917013 | 0.79 | TP53 (0.46) | PPARGPPARAFFAR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448523-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | NOVARTIS AG (CH) | 2007-08-22 | — | — | EP | claimed |