Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ILK | Q13418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128905 | 0.89 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL18416893 | 0.88 | CYP3A4 (0.56) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL30189863 | 0.88 | CYP3A4 (0.56) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL6875429 | 0.84 | TDP1 (0.56) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL2171428 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2HPGDTSHR | |
| SCHEMBL687610 | 0.81 | SMN1; SMN2 (0.66) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL3042793 | 0.81 | CYP3A4 (0.53) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL21902256 | 0.81 | CYP3A4 (0.53) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL3037816 | 0.81 | CYP3A4 (0.53) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL106320 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136812-A | Compound for targeted degradation of transcription factor KLF5 and application thereof | 昆明医科大学 | 2025-06-13 | — | — | CN | disclosed |
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |