Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.69 |
| ▸ | POLB | P06746 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651050 | 0.86 | MEN1 (0.74) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL13185637 | 0.85 | POLB (0.70) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL29042444 | 0.84 | MEN1 (0.72) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL10813685 | 0.83 | POLB (0.75) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL10813692 | 0.83 | POLB (0.75) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL23867550 | 0.82 | POLB (0.76) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL6816361 | 0.82 | POLB (0.73) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL19944328 | 0.82 | POLB (0.73) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL7560982 | 0.80 | MEN1 (0.66) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL19921045 | 0.79 | POLB (0.69) | MEN1KMT2APOLBSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |