Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RNF4 | P78317 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651050 | 0.87 | MEN1 (0.74) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL29042444 | 0.85 | MEN1 (0.72) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL10813692 | 0.81 | POLB (0.75) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL10813685 | 0.81 | POLB (0.75) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL5206520 | 0.80 | MEN1 (0.69) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL23867550 | 0.80 | POLB (0.76) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL6816361 | 0.80 | POLB (0.73) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL19944328 | 0.80 | POLB (0.73) | MEN1KMT2APOLBSMN1; SMN2NPC1 | |
| SCHEMBL1372329 | 0.79 | S1PR1 (0.64) | POLBRAB9AHPGDMAPT | |
| SCHEMBL1372971 | 0.79 | S1PR1 (0.64) | POLBRAB9AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |