Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019709 | 0.83 | MAPK1 (0.45) | MAPK1TDP1GABRA1GABRB2CYP3A4 | |
| SCHEMBL7922006 | 0.83 | MAPK1 (0.61) | MAPK1TDP1GABRA1GABRB2CYP3A4 | |
| SCHEMBL11521713 | 0.80 | MAPK1 (0.44) | MAPK1TDP1GABRA1GABRB2CYP3A4 | |
| SCHEMBL14254774 | 0.79 | MAPK1 (0.57) | MAPK1TDP1GABRA1GABRB2CYP3A4 | |
| SCHEMBL6330610 | 0.79 | MAPK1 (0.42) | MAPK1TDP1GABRA1GABRB2 | |
| SCHEMBL7931082 | 0.79 | MAPK1 (0.57) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL8840231 | 0.79 | MAPK1 (0.57) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL1950823 | 0.79 | MAPK1 (0.42) | MAPK1TDP1GABRA1GABRB2 | |
| SCHEMBL11322087 | 0.79 | GABRA1 (0.42) | MAPK1TDP1GABRA1GABRB2CYP3A4 | |
| SCHEMBL8641955 | 0.78 | MAPK1 (0.50) | MAPK1TDP1GABRA1GABRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490394-B1 | METHOD AND APPARATUS FOR THE IDENTIFICATION AND QUALIFICATION OF BIOMOLECULES | PERSEPTIVE BIOSYSTEMS INC (US) | 2007-11-07 | — | — | EP | disclosed |
| US-7166441-B2 | Method and apparatus for the identification and quantification of biomolecules | PERSEPTIVE BIOSYSTEMS INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-6787330-B1 | USING POLYACRYLAMIDE GEL ELECTROPHORESIS (PAGE); PROTEOMICS; BLOT ANALYSIS | UNIVERSITY OF GENEVA (CH) | 2004-09-07 | — | — | US | disclosed |
| EP-1147414-B1 | METHOD AND KIT FOR IDENTIFYING OR CHARACTERISING POLYPEPTIDES | UNIV GENEVE (CH) | 2004-06-09 | — | — | EP | disclosed |
| US-6632339-B1 | Electroblotting separated polypeptides from electrophoresis gel through hydrophilic membrane with immobilized cleaving reagent so polypeptides are cleaved into fragments, collecting on hydrophobic member, identifying fragments | UNIVERSITY OF GENEVA (CH) | 2003-10-14 | — | — | US | disclosed |
| US-20030175844-A1 | Method and apparatus for the identification and quantification of biomolecules | APPLIED BIOSYSTEMS, LLC | 2003-09-18 | — | — | US | disclosed |
| US-6221626-B1 | HYDROPHILIC MEMBRANE SUITABLE FOR USE IN ELECTROBLOTTING OF POLYPEPTIDES SEPARATED ON A GEL, SAID MEMBRANE HAVING ONE POLYPEPTIDE-CLEAVING REAGENT IMMOBILIZED THEREON, WHEREIN SAID REAGENT GENERATES FRAGMENTS OF THE SEPARATED POLYPEPTIDE | UNIVERSITY OF GENEVA | 2001-04-24 | — | — | US | disclosed |