SCHEMBL5206655

SCHEMBL5206655

N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)C1CCCCC1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 18/20 0.63
DPP8 Q6V1X1 3/20 0.63
DPP7 Q9UHL4 2/20 0.63
DPP9 Q86TI2 1/20 0.60
FAP Q12884 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5208078 0.99 DPP4 (0.61) DPP4DPP8DPP7DPP9FAP
SCHEMBL6165642 0.79 DPP4 (0.86) DPP4DPP8DPP7DPP9FAP
SCHEMBL6041034 0.77 DPP4 (1.00) DPP4DPP8DPP7DPP9FAP
SCHEMBL6041038 0.77 DPP4 (1.00) DPP4DPP8DPP7DPP9FAP
SCHEMBL14392566 0.77 DPP4 (1.00) DPP4DPP8DPP7DPP9FAP
SCHEMBL5202315 0.76 DPP4 (0.76) DPP4DPP8DPP7DPP9FAP
SCHEMBL6754510 0.76 DPP4 (0.76) DPP4DPP8DPP7DPP9FAP
SCHEMBL3164971 0.75 DPP4 (0.55) DPP4DPP8DPP7DPP9FAP
SCHEMBL6751803 0.75 DPP4 (0.55) DPP4DPP8DPP7DPP9FAP
SCHEMBL14790968 0.75 DPP4 (0.66) DPP4DPP8DPP7DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746086-A1 Cyanopyrrolidine derivatives TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-01-24 EP disclosed