Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203143 | 0.85 | CNR2 (0.43) | SLC2A1LMNANPSR1HTTHTR2A | |
| SCHEMBL4862806 | 0.75 | SLC2A1 (0.31) | SLC2A1 | |
| SCHEMBL4859827 | 0.75 | SLC2A1 (0.61) | SLC2A1ALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL5206911 | 0.74 | SLC2A1 (0.57) | SLC2A1ALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL14181452 | 0.73 | SLC2A1 (0.57) | SLC2A1ALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL5202930 | 0.73 | SLC2A1 (0.59) | SLC2A1ALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL4859525 | 0.71 | SLC2A1 (0.63) | SLC2A1ALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL5202357 | 0.71 | SLC2A1 (0.55) | SLC2A1ALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL4853409 | 0.71 | SLC2A1 (0.50) | SLC2A1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL5206324 | 0.70 | SLC2A1 (0.50) | SLC2A1ALDH1A1LMNATDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654253-B1 | SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-01-03 | — | — | EP | claimed |