Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.61 |
| ▸ | MEN1 | O00255 | 11/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572863 | 0.91 | RAB9A (0.71) | KMT2AMEN1NPC1RAB9AMAOB | |
| SCHEMBL1098345 | 0.87 | RAB9A (0.77) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL14890950 | 0.85 | RAB9A (0.74) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL9508626 | 0.84 | KMT2A (0.63) | KMT2AMEN1NPC1RAB9AMAOA | |
| SCHEMBL11795069 | 0.84 | RAB9A (0.68) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL11782142 | 0.83 | KMT2A (0.83) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL13885530 | 0.83 | KMT2A (0.62) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL11135996 | 0.83 | KMT2A (0.71) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL8987227 | 0.83 | KMT2A (0.87) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL8987230 | 0.83 | KMT2A (0.63) | KMT2AMEN1NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362855-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2007-10-03 | — | — | EP | disclosed |
| CN-1273467-C | Beta-lactam compounds, process for producing the same and serum cholesterol-lowering agents containing the same | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2006-09-06 | — | — | CN | disclosed |
| US-7045515-B2 | β-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| CN-1492865-A | Beta-lactam compounds, process for producing the same and serum cholesterol-lowering agents containing the same | ������ҩ��ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| US-20040063929-A1 | Beta-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1362855-A1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063929-A1 | Beta-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | HMGCR, NCEH1, CETP | KMT2A 3038/4885MEN1 1264/4885NPC1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.