Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.46 |
| ▸ | APLNR | P35414 | 5/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206941 | 0.88 | MAPK14 (0.40) | MAPK14APLNRP2RX3 | |
| SCHEMBL5240579 | 0.88 | MAPK14 (0.39) | MAPK14APLNRP2RX3 | |
| SCHEMBL5202726 | 0.83 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL3523763 | 0.82 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL5241553 | 0.82 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL3519143 | 0.78 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL3518588 | 0.77 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL5202236 | 0.77 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL5204144 | 0.76 | MAPK14 (0.41) | MAPK14 | |
| SCHEMBL3523091 | 0.75 | MAPK14 (0.48) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |