SCHEMBL5207353

SCHEMBL5207353

CCCC=CCCc1[c]cccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5206720 0.89 CYP1A2 (0.35)
SCHEMBL5202026 0.89 HIF1A (0.33)
SCHEMBL615502 0.89 EPHX2 (0.31)
SCHEMBL28731461 0.89 EPHX2 (0.31)
SCHEMBL1072076 0.89 EPHX2 (0.31)
SCHEMBL5203865 0.88 SOAT2 (0.39)
SCHEMBL1452127 0.88 HIF1A (0.38)
SCHEMBL1452128 0.88 HIF1A (0.38)
SCHEMBL5203529 0.86 SOAT2 (0.41)
SCHEMBL5204399 0.86 SOAT2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980867-B1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES (JP) 2007-08-08 EP disclosed
US-6100292-A Ketone derivatives and their medical applications TORAY INDUSTRIES, INC. (JP) 2000-08-08 US disclosed
EP-0980867-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2000-02-23 EP disclosed