Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209815 | 0.89 | TACR1 (0.41) | MAPTLMNAPOLBMAPK1HTT | |
| SCHEMBL5214208 | 0.86 | TACR1 (0.46) | MAPTLMNAPOLBMAPK1HTT | |
| SCHEMBL5210928 | 0.84 | RXRA (0.46) | ALDH1A1KDM4ENPC1CYP1A2CYP3A4 | |
| SCHEMBL5214817 | 0.82 | KDM4E (0.40) | MAPTLMNAPOLBHTTALDH1A1 | |
| SCHEMBL5209029 | 0.78 | POLB (0.47) | MAPTLMNAPOLBMAPK1HTT | |
| SCHEMBL5210227 | 0.78 | POLB (0.41) | MAPTLMNAPOLBMAPK1HTT | |
| SCHEMBL5209589 | 0.76 | POLB (0.50) | MAPTLMNAPOLBMAPK1HTT | |
| SCHEMBL5211815 | 0.76 | POLB (0.47) | MAPTLMNAPOLBMAPK1HTT | |
| SCHEMBL5210396 | 0.76 | MEN1 (0.43) | MAPTLMNAPOLBHTTALDH1A1 | |
| SCHEMBL5207233 | 0.75 | POLB (0.37) | MAPTPOLBTNKSPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | claimed |
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |