Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858972 | 0.90 | F10 (0.69) | F10KCNH2 | |
| SCHEMBL14394521 | 0.90 | F10 (0.81) | F10KCNH2 | |
| SCHEMBL5202745 | 0.89 | F10 (0.59) | F10KCNH2 | |
| SCHEMBL5207874 | 0.89 | F10 (0.60) | F10KCNH2 | |
| Hydrochloric Acid SCHEMBL5204818 | 0.88 | F10 (0.80) | F10KCNH2 | |
| SCHEMBL4848558 | 0.88 | F10 (0.74) | F10KCNH2 | |
| SCHEMBL5205754 | 0.87 | F10 (0.64) | F10 | |
| SCHEMBL4849798 | 0.85 | F10 (0.65) | F10KCNH2 | |
| SCHEMBL4853041 | 0.85 | F10 (0.57) | F10KCNH2 | |
| Water SCHEMBL5206289 | 0.85 | F10 (0.55) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307444-B1 | SUBSTITUTED HETEROCYCLIC AMIDES | LILLY CO ELI (US) | 2007-10-03 | — | — | EP | disclosed |
| US-7160878-B2 | Substituted heterocyclic amides | ELI LILLY AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160878-B2 | Substituted heterocyclic amides | ELI LILLY AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160878-B2 | Substituted heterocyclic amides | ELI LILLY AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-20040097491-A1 | Substituted heterocyclic amides | HERRON DAVID KENT (US) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097491-A1 | Substituted heterocyclic amides | F12, F11, F8 | F10 11/4885KCNH2 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.