⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9124720 | 0.90 | MAPK1 (0.38) | — | |
| SCHEMBL5276371 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL4964191 | 0.73 | — | — | |
| SCHEMBL687481 | 0.72 | — | — | |
| SCHEMBL107616 | 0.71 | — | — | |
| SCHEMBL14128906 | 0.71 | — | — | |
| SCHEMBL29034411 | 0.70 | — | — | |
| SCHEMBL7875334 | 0.69 | — | — | |
| SCHEMBL4196105 | 0.69 | — | — | |
| SCHEMBL1601687 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680408-B2 | REACTING S-METHYL NITROISOTHIOUREA WITH ALPHA-ETHYLBENZYLAMINE IN THE PRESENCE OF WATER AND ETHANOL MIXTURES TO FORM 1-(ALPHA-ETHYLBENZYL)-3-NITROGUANIDINE, USED AS PREEMERGENCE HERBICIDES | BAYER CROPSCIENCE LP | 2004-01-20 | — | — | US | claimed |
| US-20030236168-A1 | PROCESSES FOR THE PREPARATION OF ALPHA-SUBSTITUTED BENZYLNITROGUANIDINES | BAYER CORPORATION | 2003-12-25 | — | — | US | claimed |
| CN-1050186-A | Guanidine derivative | CIBA GEIGY AG (CH) | 1991-03-27 | — | — | CN | claimed |
| JP-10007648-A | — | — | None | — | — | JP | disclosed |
| EP-3853202-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ModernaTX, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061367-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| CN-110520409-A | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX INC | 2019-11-29 | — | — | CN | disclosed |
| CN-109475565-A | CGAS agonist compounds | 免疫传感器公司 | 2019-03-15 | — | — | CN | disclosed |
| WO-2018170306-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2018-09-20 | — | — | WO | disclosed |
| EP-1187833-B1 | METHOD OF PRODUCING THIAMETHOXAM | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-06 | — | — | EP | disclosed |
| WO-2005117882-A9 | HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | INCYTE CORP (US) | 2007-03-01 | — | — | WO | disclosed |
| US-5245040-A | PROCESS FOR THE PREPARATION OF NITROGUANIDINE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| CN-1059719-A | Novel substituted guanidine derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-03-25 | — | — | CN | disclosed |
| CN-1057833-A | The nitroethylene of Arthropodicidal and nitroguanidine | DU PONT (US) | 1992-01-15 | — | — | CN | disclosed |
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |
| CN-1050186-A | Guanidine derivative | CIBA GEIGY AG (CH) | 1991-03-27 | — | — | CN | disclosed |
| EP-0049618-B1 | IMPROVEMENTS IN OR RELATING TO 2,4-DISUBSTITUTED THIAZOLE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4382090-A | N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| EP-0049618-A1 | Improvements in or relating to 2,4-disubstituted thiazole derivatives | ELI LILLY AND COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4137237-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |