Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.45 |
| ▸ | LCAT | P04180 | 6/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5210095 | 0.99 | HRH3 (0.44) | HRH3LCATTIPARPCHRM2CHRM4 | |
| SCHEMBL5212095 | 0.81 | HRH3 (0.48) | HRH3LCATCHRM4 | |
| SCHEMBL5210771 | 0.81 | HRH3 (0.55) | HRH3 | |
| Hydrochloric Acid SCHEMBL5210894 | 0.81 | HRH3 (0.54) | HRH3 | |
| Hydrochloric Acid SCHEMBL5210871 | 0.81 | HRH3 (0.47) | HRH3LCATCHRM4 | |
| SCHEMBL5208707 | 0.80 | HRH3 (0.46) | HRH3LCAT | |
| SCHEMBL5211979 | 0.80 | HRH3 (0.48) | HRH3TIPARP | |
| Hydrochloric Acid SCHEMBL5215054 | 0.79 | HRH3 (0.47) | HRH3TIPARP | |
| Hydrochloric Acid SCHEMBL5212833 | 0.79 | HRH3 (0.45) | HRH3LCAT | |
| SCHEMBL5208552 | 0.77 | HRH3 (0.43) | HRH3LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |