Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192707 | 0.84 | NOS2 (0.57) | NOS2 | |
| SCHEMBL7125931 | 0.78 | NOS2 (0.52) | NOS2 | |
| SCHEMBL5190376 | 0.78 | NOS2 (0.67) | NOS2 | |
| SCHEMBL5195287 | 0.75 | NOS2 (0.63) | NOS2 | |
| SCHEMBL5191695 | 0.75 | NOS2 (0.54) | NOS2 | |
| SCHEMBL5191633 | 0.74 | NOS2 (0.67) | NOS2 | |
| SCHEMBL5191307 | 0.74 | NOS2 (0.67) | NOS2 | |
| SCHEMBL5189685 | 0.73 | NOS2 (0.61) | NOS2 | |
| SCHEMBL5191464 | 0.72 | NOS2 (0.48) | NOS2 | |
| SCHEMBL5192931 | 0.72 | NOS2 (0.77) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |