Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684541 | 0.93 | HTR2A (0.57) | HTR2ADRD2DRD3RECQLSMN1; SMN2 | |
| SCHEMBL4686682 | 0.92 | HTR2A (0.58) | HTR2ADRD2DRD3ADRA1ARECQL | |
| SCHEMBL4683575 | 0.91 | DRD2 (0.53) | HTR2ADRD2DRD3ADRA1AHTR7 | |
| SCHEMBL4683531 | 0.90 | DRD2 (0.55) | HTR2ADRD2DRD3ADRA1ARECQL | |
| Hydrochloric Acid SCHEMBL4690031 | 0.90 | DRD2 (0.53) | HTR2ADRD2DRD3ADRA1AHTR7 | |
| SCHEMBL4687730 | 0.85 | HTR2A (0.57) | HTR2ADRD2DRD3SMN1; SMN2HTR2C | |
| SCHEMBL4686307 | 0.83 | DRD2 (0.51) | DRD2DRD3ADRA1ASMN1; SMN2HTR7 | |
| SCHEMBL4687609 | 0.83 | DRD2 (0.52) | DRD2DRD3ADRA1ASMN1; SMN2HTR7 | |
| SCHEMBL4684299 | 0.82 | DRD2 (0.54) | HTR2ADRD2DRD3ADRA1ASMN1; SMN2 | |
| SCHEMBL4683539 | 0.82 | HTR2A (0.52) | HTR2ADRD2DRD3ADRA1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828125-A1 | ARYLPIPERAZINE DERIVATIVES AND THEIR USE AS LIGANGS SELECTIVE OF THE DOPAMINE D3 RECEPTOR | BIOPROJET (FR) | 2007-09-05 | — | — | EP | claimed |
| WO-2006058993-A1 | ARYLPIPERAZINE DERIVATIVES AND THEIR USE AS LIGANDS SELECTIVE OF THE DOPAMINE D3 RECEPTOR | BIOPROJET (FR) | 2006-06-08 | — | — | WO | claimed |