Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.50 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210119 | 0.97 | HRH3 (0.55) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5209386 | 0.86 | KMT2A (0.57) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL5213050 | 0.85 | KMT2A (0.56) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5209549 | 0.84 | L3MBTL3 (0.70) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5212856 | 0.82 | L3MBTL3 (0.68) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5208671 | 0.82 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5209775 | 0.82 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5210695 | 0.82 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL5213593 | 0.81 | HRH3 (0.52) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5208300 | 0.81 | L3MBTL3 (0.62) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |