Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933310 | 0.94 | CCR2 (0.44) | CCR2LMNAMAPTMEN1KMT2A | |
| SCHEMBL5208975 | 0.82 | CCR2 (0.50) | CCR2LMNAMAPTMEN1KMT2A | |
| SCHEMBL5208961 | 0.82 | CCR2 (0.50) | CCR2LMNAMAPTMEN1KMT2A | |
| Iodide SCHEMBL5206286 | 0.82 | CCR2 (0.73) | CCR2 | |
| Iodide SCHEMBL5206291 | 0.82 | CCR2 (0.73) | CCR2 | |
| SCHEMBL7681268 | 0.73 | CCR2 (0.46) | CCR2MAPTMEN1KMT2ATRPV1 | |
| SCHEMBL7681272 | 0.73 | CCR2 (0.46) | CCR2MAPTMEN1KMT2ATRPV1 | |
| SCHEMBL7682396 | 0.73 | MAPK1 (0.49) | CCR2LMNAMAPTNPC1EGFR | |
| SCHEMBL7682398 | 0.73 | MAPK1 (0.49) | CCR2LMNAMAPTNPC1EGFR | |
| SCHEMBL19003304 | 0.73 | ABL1 (0.58) | LMNAMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |