SCHEMBL52094

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL85925	0.85	GPR35 (0.50)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452250	0.83	KDM4E (0.58)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452319	0.82	HPGD (0.57)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452298	0.82	HPGD (0.57)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452228	0.82	HPGD (0.57)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452206	0.82	HPGD (0.69)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452283	0.82	HPGD (0.57)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL13265695	0.80	PARP1 (0.50)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452297	0.80	GPR35 (0.54)	HPGDGPR35MEN1GRIN2DGRIN3B
	SCHEMBL9452204	0.78	HPGD (0.53)	HPGDGPR35MEN1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.