Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203848 | 0.78 | ALDH1A1 (0.51) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL23399438 | 0.76 | NR4A3 (0.53) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL2123401 | 0.76 | NR4A3 (0.49) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL773204 | 0.76 | NR4A3 (0.78) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL33201 | 0.76 | NR4A3 (0.49) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL3839947 | 0.76 | MAPK1 (0.54) | MAPTMAPK1RAB9APKM | |
| SCHEMBL13593554 | 0.75 | ALDH1A1 (0.63) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL33204 | 0.74 | NR4A3 (0.47) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL26042 | 0.74 | NR4A3 (0.54) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL12385631 | 0.74 | NR4A3 (0.47) | NR4A3ALDH1A1MAPTMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | claimed |
| EP-1654253-B1 | SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |