Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690135 | 0.88 | MAPK1 (0.56) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL22499865 | 0.88 | MAPK1 (0.56) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL20708027 | 0.87 | POLB (0.61) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL29566202 | 0.80 | APLNR (0.43) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL931824 | 0.80 | APLNR (0.43) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL17331919 | 0.80 | POLB (0.50) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL12985766 | 0.80 | MEN1 (0.43) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL1604959 | 0.78 | GAA (0.55) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL22499955 | 0.78 | KMT2A (0.50) | POLBGAASMN1; SMN2KMT2AHPGD | |
| SCHEMBL17765262 | 0.78 | MEN1 (0.43) | POLBGAASMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156048-B1 | Heteroaroyl-isoxazoles and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2007-08-08 | — | — | EP | disclosed |
| EP-0588357-B1 | Isoxazoles derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| CN-1045439-C | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1999-10-06 | — | — | CN | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1085219-A | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1994-04-13 | — | — | CN | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |