Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | F3 | P13726 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207722 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL5207287 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL8137426 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL5204841 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL5204053 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL5207611 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL16892578 | 0.98 | SOAT2 (0.41) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL7542286 | 0.95 | PPARA (0.42) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL5207134 | 0.95 | CYP1A2 (0.35) | SOAT2SOAT1EPHX2FAAHPPARA | |
| SCHEMBL5203865 | 0.93 | SOAT2 (0.39) | SOAT2SOAT1EPHX2FAAHPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |