SCHEMBL5209743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5058555	0.87	ABCB1 (0.58)	ABCB1SMN1; SMN2HPGDCYP3A4CYP2C9
	SCHEMBL5062407	0.83	ABCB1 (0.53)	ABCB1SMN1; SMN2HPGDCYP3A4
	SCHEMBL5057388	0.82	ABCB1 (0.56)	ABCB1SMN1; SMN2HPGDCYP3A4CYP2C9
	SCHEMBL5056941	0.82	HPGD (0.56)	ABCB1SMN1; SMN2HPGDCYP3A4CYP2C9
	SCHEMBL5064387	0.82	HPGD (0.63)	ABCB1SMN1; SMN2HPGDCYP3A4POLB
	SCHEMBL5058463	0.82	ABCB1 (0.49)	ABCB1SMN1; SMN2HPGDNPC1
	SCHEMBL668612	0.81	ABCB1 (0.71)	ABCB1SMN1; SMN2HPGDCYP3A4
	SCHEMBL9230670	0.81	LPAR1 (0.42)	ABCB1SMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL9714143	0.80	ABCB1 (0.83)	ABCB1SMN1; SMN2CYP3A4CYP2C9MEN1
	SCHEMBL10139352	0.80	HPGD (0.54)	ABCB1SMN1; SMN2HPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.