Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416592 | 0.82 | ADRB2 (0.42) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL5209743 | 0.81 | ABCB1 (0.57) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18091865 | 0.69 | NPC1 (0.48) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9102505 | 0.68 | ABCB1 (0.41) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8252765 | 0.68 | GAA (0.47) | MAPTTSHRNPSR1GAA | |
| SCHEMBL18091856 | 0.67 | ABCB1 (0.43) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18091874 | 0.67 | MAPT (0.43) | MEN1KMT2ASMN1; SMN2POLBHTT | |
| SCHEMBL18091860 | 0.67 | RAB9A (0.47) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5058555 | 0.67 | ABCB1 (0.58) | SMN1; SMN2ABCB1 | |
| SCHEMBL16506926 | 0.66 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |