Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204958 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAADORA1ADORA3ADORA2A | |
| SCHEMBL5207681 | 0.78 | KMT2A (0.36) | ALDH1A1LMNAKMT2AADORA1ADORA3 | |
| SCHEMBL14834449 | 0.78 | IDO1 (0.44) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL5203636 | 0.77 | NPC1 (0.45) | KMT2AMEN1MAPTPOLB | |
| SCHEMBL5203627 | 0.77 | NPC1 (0.45) | KMT2AMEN1MAPTPOLB | |
| SCHEMBL15732597 | 0.76 | POLB (0.43) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL242610 | 0.72 | ADORA1 (0.52) | ADORA1ADORA3ADORA2AADORA2BTDP1 | |
| SCHEMBL18340878 | 0.72 | KMT2A (0.45) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL5207569 | 0.71 | KMT2A (0.41) | ALDH1A1LMNAKMT2AADORA1ADORA2A | |
| SCHEMBL5203657 | 0.69 | CKS1B (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306085-B1 | 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor | NEUROGEN CORP (US) | 2007-02-14 | — | — | EP | claimed |