⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168895 | 1.00 | — | — | |
| SCHEMBL2154663 | 0.72 | — | — | |
| SCHEMBL6294448 | 0.72 | — | — | |
| Carbon Dioxide SCHEMBL4942576 | 0.67 | — | — | |
| SCHEMBL10734809 | 0.67 | — | — | |
| Carbon Dioxide SCHEMBL1724288 | 0.62 | — | — | |
| Carbon Dioxide SCHEMBL7713031 | 0.61 | — | — | |
| Carbon Dioxide SCHEMBL241039 | 0.61 | — | — | |
| Carbon Dioxide SCHEMBL71642 | 0.61 | — | — | |
| Carbon Dioxide SCHEMBL916 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337512-B1 | (4-ACYLAMINOPIPERIDIN-1-YL) ACETAMIDES AS NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-06-13 | — | — | EP | claimed |
| US-6664253-B2 | N-phenethyl-2-aryl-2-(4-(oxy-or amino-carbonylamino)piperidin-1-yl)acetamide derivatives | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-16 | — | — | US | claimed |
| EP-1337512-A1 | (4-ACYLAMINOPIPERIDIN-1-YL) ACETAMIDES AS NEUROKININ ANTAGONISTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-08-27 | — | — | EP | claimed |
| US-20020115666-A1 | Neurokinin antagonists | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-22 | — | — | US | claimed |
| WO-2002032866-A1 | (4-ACYLAMINOPIPERIDIN-1-YL) ACETAMIDES AS NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | claimed |
| EP-1337512-B1 | (4-ACYLAMINOPIPERIDIN-1-YL) ACETAMIDES AS NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-06-13 | — | — | EP | disclosed |
| US-6664253-B2 | N-phenethyl-2-aryl-2-(4-(oxy-or amino-carbonylamino)piperidin-1-yl)acetamide derivatives | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-16 | — | — | US | disclosed |
| EP-1337512-A1 | (4-ACYLAMINOPIPERIDIN-1-YL) ACETAMIDES AS NEUROKININ ANTAGONISTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-08-27 | — | — | EP | disclosed |
| US-20020115666-A1 | Neurokinin antagonists | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-22 | — | — | US | disclosed |
| WO-2002032866-A1 | (4-ACYLAMINOPIPERIDIN-1-YL) ACETAMIDES AS NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |