Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203389 | 0.91 | HRH3 (0.38) | HRH3CASRALDH1A1MAPK1BRAF | |
| SCHEMBL5203692 | 0.86 | TNFRSF1A (0.37) | HRH3CASRFGFR1ALDH1A1CYP1A2 | |
| SCHEMBL5207725 | 0.82 | ALDH1A1 (0.39) | HRH3ALDH1A1BRD4FYN | |
| SCHEMBL5207045 | 0.82 | HRH3 (0.42) | HRH3ALDH1A1FYN | |
| SCHEMBL5207852 | 0.80 | FYN (0.43) | BRD4FYN | |
| SCHEMBL5205364 | 0.79 | MEN1 (0.41) | HRH3FYN | |
| SCHEMBL5203407 | 0.78 | FYN (0.40) | BRD4FYN | |
| SCHEMBL5204659 | 0.78 | FYN (0.41) | BRD4FYN | |
| SCHEMBL5205586 | 0.77 | HRH3 (0.34) | HRH3ALDH1A1MAPK1FYN | |
| SCHEMBL5210597 | 0.77 | HRH3 (0.38) | HRH3ALDH1A1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |