Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 19/20 | 0.58 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193371 | 0.89 | NOS2 (0.66) | NOS2NOS1 | |
| SCHEMBL5211134 | 0.88 | NOS2 (0.65) | NOS2NOS1 | |
| SCHEMBL6324458 | 0.88 | NOS2 (0.70) | NOS2NOS1 | |
| SCHEMBL5190289 | 0.84 | NOS2 (0.74) | NOS2NOS1 | |
| SCHEMBL5194288 | 0.83 | NOS2 (0.65) | NOS2NOS1 | |
| SCHEMBL5189863 | 0.82 | NOS2 (0.82) | NOS2NOS1 | |
| SCHEMBL5190492 | 0.81 | NOS2 (0.74) | NOS2NOS1 | |
| SCHEMBL5190216 | 0.81 | NOS2 (0.45) | NOS2 | |
| SCHEMBL5191345 | 0.80 | NOS2 (0.70) | NOS2NOS1 | |
| SCHEMBL5193325 | 0.79 | NOS2 (0.66) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754703-A2 | N-Heterocyclic derivatives as nos inhibitors | Berlex, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |