SCHEMBL5211279

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5214497	0.99	CKS1B (0.86)	CKS1BSKP1SKP2CNR1NR1I2
	Selexipag SCHEMBL674122	0.92	CKS1B (1.00)	CKS1BSKP1SKP2CNR1NR1I2
	Selexipag SCHEMBL29360518	0.92	CKS1B (1.00)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL5212176	0.91	CKS1B (0.84)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL19820816	0.91	CKS1B (0.98)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL5213604	0.91	CKS1B (0.84)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL5210832	0.90	CKS1B (0.83)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL5211167	0.90	CKS1B (0.83)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL5210755	0.90	CKS1B (0.83)	CKS1BSKP1SKP2CNR1NR1I2
	SCHEMBL12442140	0.89	NR1I2 (0.81)	CKS1BSKP1SKP2CNR1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.