Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374513 | 0.91 | MAPK1 (0.60) | ABCG2ABCC1ABCB1L3MBTL1HPGD | |
| SCHEMBL4341820 | 0.83 | MAPT (0.72) | MAPK1ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL4353650 | 0.81 | MAPT (0.63) | HPGDALOX12MAPK1ALDH1A1TDP1 | |
| SCHEMBL5244119 | 0.80 | MEN1 (0.68) | ABCG2L3MBTL1HPGDALOX12MAPK1 | |
| SCHEMBL38659285 | 0.80 | MEN1 (0.68) | L3MBTL1HPGDALOX12MAPK1ALDH1A1 | |
| SCHEMBL23579273 | 0.80 | MEN1 (0.57) | L3MBTL1HPGDALOX12MAPK1ALDH1A1 | |
| SCHEMBL9793524 | 0.80 | FFAR4 (0.62) | L3MBTL1HPGDALOX12MAPK1ALDH1A1 | |
| SCHEMBL9650509 | 0.80 | MEN1 (0.68) | L3MBTL1HPGDALOX12MAPK1ALDH1A1 | |
| SCHEMBL28592893 | 0.80 | L3MBTL1 (0.51) | ABCG2ABCB1L3MBTL1HPGDALOX12 | |
| SCHEMBL6881421 | 0.79 | HPGD (0.58) | ABCG2ABCC1ABCB1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799634-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |