Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.61 |
| ▸ | PTGIR | P43119 | 2/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 3/20 | 0.47 |
| ▸ | SKP1 | P63208 | 3/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211664 | 0.87 | PTGIR (0.51) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5211988 | 0.84 | TBXA2R (0.58) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5217386 | 0.82 | TBXA2R (0.59) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5212130 | 0.80 | KDM1A (0.50) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5214202 | 0.80 | NR1I2 (0.57) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5216034 | 0.80 | PTGIR (0.54) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5214690 | 0.79 | TBXA2R (0.62) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5210867 | 0.78 | NR1I2 (0.77) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5218171 | 0.78 | PTGIR (0.55) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5210823 | 0.78 | NR1I2 (0.72) | NR1I2ADORA3TBXA2RAGTR1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205302-B2 | Anticoagulants; antilipemic agents; cardiovascular disorders | NIPPON SHINYAKU CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| EP-1400518-B1 | HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-20040102436-A1 | Heterocyclic compound derivatives and medicines | NIPPON SHINYAKU CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1400518-A1 | HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES | Nippon Shinyaku Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102436-A1 | Heterocyclic compound derivatives and medicines | CNR2, CNR1, GPR55 | NR1I2 8/4885ADORA3 279/4885TBXA2R 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.