Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210608 | 0.77 | SCD (0.49) | MAOBMAOASCDHRH4ALDH1A1 | |
| SCHEMBL27599390 | 0.71 | MAOB (0.44) | MAOBMAOASCDL3MBTL1HRH4 | |
| SCHEMBL19994617 | 0.69 | MAOB (0.58) | MAOBMAOAL3MBTL1NFE2L2ALDH1A1 | |
| SCHEMBL19994618 | 0.69 | MAOB (0.58) | MAOBMAOAL3MBTL1NFE2L2ALDH1A1 | |
| SCHEMBL1475061 | 0.68 | MAOB (0.53) | MAOBMAOAL3MBTL1ALDH1A1 | |
| SCHEMBL1475057 | 0.68 | MAOB (0.53) | MAOBMAOAL3MBTL1ALDH1A1 | |
| SCHEMBL20015327 | 0.66 | MAOA (0.54) | MAOBMAOA | |
| SCHEMBL14261782 | 0.66 | MAOA (0.54) | MAOBMAOA | |
| SCHEMBL20015574 | 0.66 | MAOA (0.56) | MAOBMAOANFE2L2 | |
| SCHEMBL27599453 | 0.66 | MAOA (0.56) | MAOBMAOANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484327-B1 | NITROGENOUS HETEROCYCLIC COMPOUND AND MEDICINE THEREOF | EISAI R&D MAN CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |