Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 3/20 | 0.31 |
| ▸ | FNTB | P49356 | 3/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211288 | 0.84 | FLT1 (0.35) | FLT1KDR | |
| SCHEMBL5208094 | 0.84 | POLB (0.36) | FLT1KDR | |
| SCHEMBL5208158 | 0.82 | FLT1 (0.35) | FLT1KDR | |
| Hydrochloric Acid SCHEMBL5207976 | 0.82 | FLT1 (0.35) | FLT1KDR | |
| SCHEMBL5211498 | 0.82 | FLT1 (0.32) | SLC16A3FLT1KDR | |
| SCHEMBL5210884 | 0.81 | ATM (0.34) | FLT1KDR | |
| SCHEMBL14564994 | 0.79 | FLT1 (0.33) | FLT1KDR | |
| SCHEMBL5244657 | 0.79 | FLT1 (0.37) | FLT1KDR | |
| SCHEMBL5209929 | 0.79 | FLT1 (0.32) | FLT1KDR | |
| SCHEMBL5207787 | 0.78 | FLT1 (0.33) | FLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401826-B1 | PYRAZOLE DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | claimed |