Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.39 |
| ▸ | LCAT | P04180 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5211669 | 0.99 | HRH3 (0.47) | HRH3CHEK1LCATTACR3 | |
| SCHEMBL4031793 | 0.86 | HRH3 (0.42) | HRH3CHEK1LCATTACR3 | |
| SCHEMBL5212927 | 0.81 | HRH3 (0.64) | HRH3 | |
| SCHEMBL5208629 | 0.81 | HRH3 (0.48) | HRH3LCAT | |
| Hydrochloric Acid SCHEMBL5211632 | 0.80 | HRH3 (0.63) | HRH3GPR119 | |
| Hydrochloric Acid SCHEMBL5210549 | 0.80 | HRH3 (0.47) | HRH3LCATTACR3 | |
| SCHEMBL3863105 | 0.79 | HRH3 (0.62) | HRH3TACR3 | |
| Hydrochloric Acid SCHEMBL3859424 | 0.78 | HRH3 (0.61) | HRH3TACR3 | |
| SCHEMBL5213183 | 0.78 | HRH3 (0.61) | HRH3LCAT | |
| SCHEMBL5210405 | 0.77 | HRH3 (0.61) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | disclosed |