Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209792 | 1.00 | ADRB2 (0.39) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5943664 | 0.97 | ADRB2 (0.39) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5215049 | 0.93 | ADRB2 (0.36) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5943639 | 0.93 | ADRB2 (0.36) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5943666 | 0.92 | ADRB2 (0.36) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5213191 | 0.92 | ADRB3 (0.35) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5212239 | 0.91 | ADRB2 (0.35) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5212232 | 0.91 | ADRB2 (0.35) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5212216 | 0.90 | ADRB3 (0.36) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL5209443 | 0.90 | ADRB3 (0.38) | ADRB2ADRB1ADRB3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554264-B1 | MEDICINAL ARYLETHANOLAMINE COMPOUNDS | GLAXO GROUP LTD (GB) | 2007-08-08 | — | — | EP | disclosed |