Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTR1B | P28222 | 7/20 | 0.55 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.53 |
| ▸ | BAD | Q92934 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363163 | 0.83 | SLC6A4 (0.58) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL11021590 | 0.82 | SLC6A4 (0.57) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL10528975 | 0.81 | SLC6A4 (0.62) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL9770352 | 0.80 | KCNA3 (0.81) | SLC6A4KCNA3HRH1TDP1KMT2A | |
| SCHEMBL12305476 | 0.80 | SLC6A4 (0.54) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL20911356 | 0.80 | CNR2 (0.71) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL29865967 | 0.80 | CNR2 (0.71) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL4294120 | 0.79 | CNR2 (0.69) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL29865585 | 0.79 | CNR2 (0.69) | SLC6A4KDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL20886144 | 0.79 | CNR2 (0.69) | SLC6A4KDM4EALDH1A1HPGDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708994-B1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-08-08 | — | — | EP | disclosed |
| EP-1708994-A1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005077898-A1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2005-08-25 | — | — | WO | disclosed |