Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 6/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | OGG1 | O15527 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363163 | 0.99 | SLC6A4 (0.58) | SLC6A4KDM4EALDH1A1HPGDHRH1 | |
| SCHEMBL10804531 | 0.88 | TGM2 (0.52) | SLC6A4KDM4EALDH1A1HPGDTGM2 | |
| SCHEMBL10803446 | 0.86 | TGM2 (0.56) | KDM4EALDH1A1TGM2ITKKMT2A | |
| SCHEMBL10816283 | 0.86 | TGM2 (0.47) | SLC6A4KDM4EALDH1A1HPGDTGM2 | |
| SCHEMBL10364143 | 0.84 | NCEH1 (0.53) | ALDH1A1HPGDTGM2KMT2A | |
| SCHEMBL10362461 | 0.83 | L3MBTL1 (0.58) | SLC6A4KDM4EALDH1A1HPGDTGM2 | |
| SCHEMBL10806417 | 0.82 | TGM2 (0.49) | KDM4EALDH1A1HPGDTGM2ITK | |
| SCHEMBL10818993 | 0.82 | GAA (0.54) | KDM4EALDH1A1TGM2ITKKMT2A | |
| SCHEMBL10807055 | 0.82 | TGM2 (0.49) | KDM4EALDH1A1TGM2ITKKMT2A | |
| SCHEMBL5212699 | 0.82 | SLC6A4 (0.64) | SLC6A4KDM4EALDH1A1HPGDHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |