Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 19/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212830 | 0.89 | OPRD1 (0.73) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5212926 | 0.88 | OPRD1 (0.71) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5212935 | 0.85 | OPRD1 (0.73) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5760146 | 0.85 | OPRD1 (0.73) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL6109824 | 0.85 | OPRD1 (0.78) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5522849 | 0.85 | OPRD1 (0.74) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5215308 | 0.84 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5212829 | 0.84 | OPRD1 (0.69) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5954830 | 0.83 | OPRD1 (0.72) | OPRD1OPRM1OPRK1KCNH2ABCB11 | |
| SCHEMBL5217382 | 0.83 | OPRD1 (0.77) | OPRD1OPRM1OPRK1KCNH2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567496-B1 | PHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2007-04-11 | — | — | EP | claimed |